Platelet aggregation in chronic idiopathic thrombocytopenic purpura.
نویسندگان
چکیده
منابع مشابه
Platelet aggregation in chronic idiopathic thrombocytopenic purpura.
A method for washing platelets by albumin density gradient separation has been modified to prepare platelet rich plasma of thrombocytopenic patients for platelet aggregation studies. The concentration procedure, consisting of centrifuging platelets into a specific gravity gradient between plasma and 40-45% aqueous solution of bovine albumin, does not affect platelet aggregation adversely. Plate...
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Abstract Background Immune thrombocytopenic purpura (ITP) is a common autoimmune bleeding condition in children that is characterized by a decrease in the platelet count. The aims of this study were to define epidemiologic features of patients with primary ITP who were admitted to Mofid Children's Hospital, Tehran, Iran, in a 5-year period. Methods We retrospectively studied the records of ...
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By RIai iiD J. COHEN, LEWIS H. DENNIS AND MARCEL E. CONRAD T HE PARENTERAL ADMINISTRATION of small doses of heparin to normal adults1 and to patients with arteriosclerotic heart disease2 has no measurable effect on blood platelet economy. However, larger amounts of heparin1 and therapeutic doses of bishydroxycoumarin ( Dicumarol) distinctly prolong tile survival of circulating platelets.3’4 The...
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The vast majority of children with idiopathic thrombocytopenic purpura, dramatic though their signs may be at presentation, remit within weeks, with or perhaps despite medical attention. Such children, when referred to the Queen Elizabeth Hospital, Hackney Road by their family doctor, or appearing in the busy casualty department, have a careful history taken with particular emphasis given to th...
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The mechanism of idiopathic (autoimmune) thrombocytopenic purpura (ITP) has historically been attributed to platelet autoantibody production and the resultant platelet destruction. More recent evidence suggests a multifactorial pathogenesis. A complex picture of the immune processes involved in autoimmunity has emerged over the last decade with the identification and characterization of immunor...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1978
ISSN: 0021-9746
DOI: 10.1136/jcp.31.12.1239